Basic Information
ID: ALA1838604
Type: Binding
Description: Inhibition of GlyT1 expressed in HEK293 cells assessed as inhibition of [3H]glycine uptake by scintillation proximity binding assay
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1838604
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.45 | 4.52 | 4.52 |
| 435.47 | 5.05 | 5.05 |
| 409.44 | 4.52 | 4.52 |
| 451.47 | 4.29 | 4.29 |
| 451.47 | 4.29 | 4.29 |
| 423.46 | 4.91 | 4.91 |
| 435.47 | 4.91 | 4.91 |
| 439.46 | 4.14 | 4.14 |
| 425.44 | 3.75 | 3.75 |
| 453.49 | 4.53 | 4.53 |
| 437.45 | 3.90 | 3.90 |
| 406.86 | 5.03 | 5.03 |
| 420.89 | 5.42 | 5.42 |
| 420.89 | 5.42 | 5.42 |
| 380.82 | 4.36 | 4.36 |
| 442.92 | 4.58 | 4.58 |
| 392.88 | 5.39 | 5.39 |
| 421.88 | 5.42 | 5.42 |
| 402.44 | 4.39 | 4.39 |
| 393.48 | 3.41 | 3.41 |
| 380.44 | 3.49 | 3.49 |
| 378.46 | 4.64 | 4.64 |
| 373.40 | 3.77 | 3.77 |
| 376.41 | 3.11 | 3.11 |
| 406.86 | 5.03 | 5.03 |
| 406.86 | 5.03 | 5.03 |
| 459.54 | 4.32 | 4.32 |
| 438.48 | 4.56 | 4.56 |
| 442.51 | 4.37 | 4.37 |
| 441.52 | 4.98 | 4.98 |
| 449.50 | 5.44 | 5.44 |
| 389.50 | 5.06 | 5.06 |
| 404.51 | 5.63 | 5.63 |
| 406.55 | 5.79 | 5.79 |
| 389.50 | 5.06 | 5.06 |
| 390.49 | 4.25 | 4.25 |
| 423.94 | 6.58 | 6.58 |
| 390.48 | 5.33 | 5.33 |
| 423.46 | 4.76 | 4.76 |