Basic Information
ID: ALA1838646
Type: Binding
Description: Inhibition of C-terminal FLAG-tagged human caspase-3 expressed in HEK293 T17 cells using Ac-DEVD-AMC coumarin-120 as substrate pre-incubated for 2 hrs measured after 48 hrs by fluorometric analysis
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1838646
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 615.68 | -1.70 | -1.70 |
| 543.57 | -2.50 | -2.50 |
| 569.61 | -2.01 | -2.01 |
| 599.64 | -2.39 | -2.39 |
| 627.69 | -1.61 | -1.61 |
| 641.72 | -1.22 | -1.22 |
| 641.72 | -1.36 | -1.36 |
| 653.73 | -1.07 | -1.07 |
| 663.69 | -2.16 | -2.16 |
| 639.75 | -0.35 | -0.35 |
| 645.71 | -0.62 | -0.62 |
| 659.74 | -0.31 | -0.31 |
| 651.76 | -0.21 | -0.21 |
| 617.66 | -0.92 | -0.92 |
| 583.64 | -1.62 | -1.62 |
| 641.72 | -1.22 | -1.22 |
| 631.68 | -0.88 | -0.88 |
| 645.71 | -0.57 | -0.57 |
| 645.71 | -0.57 | -0.57 |
| 691.74 | -0.86 | -0.86 |
| 647.68 | -1.17 | -1.17 |
| 647.68 | -1.17 | -1.17 |
| 710.58 | -0.11 | -0.11 |
| 710.58 | -0.11 | -0.11 |