Basic Information
ID: ALA1840117
Type: Binding
Description: Selectivity ratio of IC50 for JAK3 to IC50 for JAK2
Activity Charts
Bioactivity
Activity Types for Assay ALA1840117
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.78 | 5.02 | 5.02 |
| 402.50 | 4.31 | 4.31 |
| 278.29 | 3.61 | 3.61 |
| 272.28 | 2.39 | 2.39 |
| 258.26 | 2.00 | 2.00 |
| 286.31 | 2.78 | 2.78 |
| 300.34 | 3.17 | 3.17 |
| 286.31 | 2.77 | 2.77 |
| 300.34 | 3.02 | 3.02 |
| 328.39 | 3.80 | 3.80 |
| 328.39 | 3.80 | 3.80 |
| 298.32 | 2.92 | 2.92 |
| 312.35 | 3.31 | 3.31 |
| 326.38 | 3.70 | 3.70 |
| 340.40 | 4.09 | 4.09 |
| 328.35 | 2.54 | 2.54 |
| 298.32 | 2.55 | 2.55 |
| 312.35 | 2.94 | 2.94 |
| 354.43 | 4.11 | 4.11 |
| 308.39 | 3.56 | 3.56 |
| 342.83 | 4.21 | 4.21 |
| 342.83 | 4.21 | 4.21 |
| 384.48 | 5.23 | 5.23 |
| 384.48 | 5.23 | 5.23 |
| 387.49 | 4.57 | 4.57 |
| 388.48 | 3.96 | 3.96 |
| 373.46 | 4.55 | 4.55 |
| 374.45 | 3.95 | 3.95 |
| 389.50 | 4.67 | 4.67 |
| 431.58 | 5.79 | 5.79 |
| 402.50 | 4.31 | 4.31 |
| 421.93 | 5.38 | 5.38 |
| 402.50 | 4.31 | 4.31 |
| 374.45 | 3.43 | 3.43 |
| 374.45 | 3.43 | 3.43 |
| 388.48 | 3.82 | 3.82 |
| 402.50 | 4.06 | 4.06 |
| 400.49 | 3.82 | 3.82 |
| 428.42 | 3.97 | 3.97 |
| 428.42 | 3.97 | 3.97 |
| 430.43 | 4.21 | 4.21 |
| 442.45 | 4.36 | 4.36 |
| 386.46 | 3.81 | 3.81 |
| 398.47 | 3.87 | 3.87 |
| 413.49 | 3.45 | 3.45 |
| 413.49 | 3.45 | 3.45 |
| 414.39 | 3.96 | 3.96 |
| 440.43 | 4.21 | 4.21 |
| 511.51 | 3.86 | 3.86 |
| 559.57 | 3.26 | 3.26 |
| 441.42 | 3.61 | 3.61 |