Basic Information
ID: ALA1840325
Type: Binding
Description: Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production at 0.3 uM pretreated 15 mins before LPS challenge measured 5 hrs post LPS challenge
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA1840325
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.43 | 2.74 | 2.74 |
| 409.45 | 1.43 | 1.43 |
| 463.42 | 2.14 | 2.14 |
| 407.47 | 2.58 | 2.58 |
| 461.44 | 3.29 | 3.29 |
| 393.45 | 2.19 | 2.19 |
| 447.42 | 2.90 | 2.90 |
| 414.49 | 2.09 | 2.09 |
| 468.46 | 2.81 | 2.81 |
| 398.49 | 2.86 | 2.86 |
| 452.46 | 3.57 | 3.57 |
| 382.42 | 2.39 | 2.39 |
| 436.39 | 3.10 | 3.10 |
| 412.52 | 3.25 | 3.25 |
| 396.45 | 2.78 | 2.78 |