Basic Information
ID: ALA1840327
Type: Binding
Description: Inhibition of TACE in human whole blood assessed as reduction of of LPS-induced TNFalpha production pretreated 15 mins before LPS challenge measured 5 hrs post LPS challenge
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA1840327
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 462.43 | 2.74 | 2.74 |
| 409.45 | 1.43 | 1.43 |
| 463.42 | 2.14 | 2.14 |
| 407.47 | 2.58 | 2.58 |
| 461.44 | 3.29 | 3.29 |
| 393.45 | 2.19 | 2.19 |
| 447.42 | 2.90 | 2.90 |