Assay Report Card

Basic Information

ID: ALA1863510

Type: Functional

Description: DNDI: Inhibition of Chagas Disease parasite Trypanosoma cruzi (Tulahuen LacZ, Clone C4), in vitro.

Organism: Trypanosoma cruzi

Strain: Tulahuen LacZ, Clone C4

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
314.753.553.55
296.763.413.41
331.204.074.07
331.204.074.07
315.204.964.96
262.743.023.02
256.312.132.13
331.204.074.07
314.753.553.55
287.300.640.64
289.555.145.14
333.734.134.13
330.214.674.67
309.804.334.33
314.225.575.57
363.775.045.04
330.214.674.67
403.394.094.09
387.824.244.24
235.072.852.85
357.781.351.35
235.312.622.62
259.102.472.47
267.311.301.30
427.963.833.83
331.204.074.07
481.906.386.38
481.384.024.02
408.934.494.49
309.804.334.33
401.793.673.67
403.454.184.18
397.325.405.40
461.614.604.60
458.484.694.69
434.514.714.71
450.563.563.56
391.813.503.50
377.795.355.35
439.485.085.08
401.473.233.23
457.504.134.13
444.464.384.38
406.914.694.69
358.873.123.12
444.513.293.29
476.524.034.03
358.706.146.14
391.523.603.60
399.974.844.84
407.922.612.61
430.355.885.88
276.773.413.41
392.654.924.92
442.904.394.39
393.393.563.56
463.944.834.83
444.464.384.38
301.823.073.07
337.394.294.29
476.454.764.76
361.885.145.14
397.902.982.98
508.475.505.50
359.862.572.57
348.204.814.81
347.203.313.31
508.475.505.50
444.464.384.38
344.245.335.33
464.514.754.75
308.814.614.61
259.743.933.93
331.204.074.07
464.942.852.85
411.914.794.79
495.954.854.85
240.312.982.98
364.754.434.43
337.353.753.75
435.376.496.49
403.513.393.39
440.544.814.81
455.395.765.76
452.983.643.64
421.935.085.08
396.462.252.25
382.441.861.86
512.504.314.31
311.773.123.12
313.183.753.75
382.874.184.18
462.404.484.48
385.345.935.93
414.863.193.19
417.543.703.70
301.804.084.08
302.793.483.48
414.873.723.72
355.833.603.60
380.902.232.23
463.393.883.88
446.504.544.54
400.954.344.34
337.343.043.04
319.794.224.22
439.485.085.08
389.423.743.74
430.944.314.31
425.894.784.78
360.852.992.99
460.963.513.51
430.355.885.88
330.172.882.88
370.883.313.31
332.215.655.65
388.873.303.30
430.455.875.87
424.594.474.47
331.204.074.07
444.464.384.38
435.495.185.18
257.764.974.97
401.943.743.74
310.783.723.72
439.924.644.64
405.423.073.07
405.953.323.32
388.883.393.39
320.783.893.89
476.934.484.48
389.904.154.15
440.474.484.48
299.813.973.97
420.925.095.09
372.394.454.45
366.194.954.95
429.883.553.55
489.024.494.49
337.234.134.13
413.454.244.24
426.994.924.92
377.853.743.74
315.853.463.46
429.494.664.66
386.933.803.80
454.505.485.48
490.554.174.17
372.353.483.48
457.805.245.24
311.773.123.12
432.515.215.21
388.463.473.47
312.762.392.39
414.512.982.98
544.525.055.05
425.335.035.03
302.793.483.48
419.494.824.82
476.454.764.76
383.863.583.58
443.473.823.82
379.912.842.84
424.522.882.88
325.804.034.03
390.893.553.55
403.454.184.18
445.926.816.81
423.454.524.52
345.403.313.31
428.953.233.23
460.534.854.85
412.974.484.48
425.574.954.95
420.945.115.11
276.773.563.56
445.954.024.02
404.903.743.74
458.484.694.69
373.933.653.65
486.594.414.41
411.514.334.33
420.945.085.08
390.795.275.27
386.326.026.02
301.804.084.08
201.222.842.84
479.916.126.12
442.973.373.37
387.893.953.95
424.594.474.47
299.414.294.29
251.114.224.22
346.382.442.44
353.733.763.76
274.804.934.93
446.524.754.75
465.885.035.03
416.205.835.83
414.452.602.60
423.413.213.21
400.954.394.39
329.832.992.99
280.253.503.50
446.906.396.39
411.434.304.30
396.462.252.25
412.904.194.19
443.474.124.12
371.405.515.51
336.244.734.73
413.463.203.20
363.775.045.04
434.514.754.75
246.703.133.13
321.764.204.20
394.904.414.41
427.944.554.55
422.924.174.17
374.443.083.08
482.984.754.75
460.534.854.85
446.524.754.75
382.853.653.65
429.836.306.30
435.495.895.89
374.674.784.78
463.916.246.24
413.905.365.36
460.344.864.86
429.564.854.85
387.405.175.17
391.904.284.28
457.504.134.13
373.823.743.74
413.836.196.19
420.484.214.21
396.493.943.94
432.474.224.22
297.752.812.81
478.953.943.94
402.934.214.21
373.884.034.03
474.004.634.63
393.924.664.66
471.534.614.61
414.452.602.60
491.565.695.69
439.485.795.79
428.543.463.46
432.474.074.07
386.462.662.66
410.883.823.82
359.372.912.91
414.484.084.08
417.543.703.70
406.923.613.61
439.924.924.92
381.765.185.18
427.834.224.22
418.494.904.90
397.473.923.92
255.323.293.29
347.314.524.52
303.753.633.63
434.993.503.50
401.473.233.23
356.783.263.26
406.924.674.67
387.914.384.38
478.953.943.94
357.934.684.68
401.473.233.23
352.823.383.38
405.904.524.52
481.906.386.38
446.905.505.50
551.003.023.02
434.975.335.33
377.852.662.66
360.412.832.83
457.504.134.13
419.484.304.30
346.432.602.60
393.943.183.18
464.494.554.55
366.871.801.80
413.463.203.20
419.933.873.87
333.313.933.93
464.494.964.96
356.451.621.62
544.525.055.05
234.663.713.71
455.395.765.76
387.894.074.07
422.913.623.62
448.346.016.01
410.492.642.64
406.924.114.11
425.454.554.55
415.884.154.15
375.654.184.18
493.563.593.59
408.453.743.74
371.363.943.94
332.234.624.62
429.453.813.81
482.485.095.09
401.473.233.23
374.674.784.78
426.395.735.73
351.285.405.40
378.784.744.74
280.154.394.39
314.753.553.55
444.464.384.38
443.474.124.12
405.913.483.48
372.422.832.83
404.443.583.58
430.944.194.19
428.482.852.85
399.933.493.49
363.775.045.04
423.924.864.86
226.282.672.67
457.504.424.42
372.422.832.83
424.522.882.88
338.793.123.12
331.322.132.13
413.836.196.19
438.915.235.23
445.926.106.10
413.905.365.36
431.895.505.50
359.862.522.52
424.914.814.81
314.753.553.55
447.455.735.73
454.505.485.48
399.443.843.84
381.523.763.76
467.985.335.33
374.674.784.78
355.833.603.60
424.914.254.25
422.483.673.67
458.533.433.43
414.484.084.08
527.975.435.43
349.404.754.75
443.334.154.15
433.504.614.61
428.482.992.99
421.403.843.84
372.903.563.56
387.923.353.35
360.422.562.56
418.422.302.30
357.244.914.91
397.902.982.98
421.934.514.51
408.225.155.15
428.464.424.42
441.983.973.97
393.873.973.97
374.852.912.91
274.804.074.07
482.574.304.30
446.906.396.39
401.873.913.91
388.903.773.77
383.882.542.54
338.793.123.12
466.554.914.91
377.852.712.71
363.435.105.10
415.464.184.18
440.903.583.58
406.453.823.82
373.933.653.65
444.464.384.38
417.554.794.79
344.852.772.77
414.484.084.08
431.574.014.01
403.513.393.39
353.854.814.81
438.464.114.11
421.464.654.65
431.895.505.50
372.394.904.90
345.352.522.52
409.894.424.42
391.784.674.67
442.904.394.39
349.285.655.65
331.754.304.30
407.443.323.32
314.225.575.57
438.934.324.32
353.854.814.81
400.492.972.97
482.485.095.09
396.275.935.93
338.844.624.62
372.353.483.48
425.574.954.95
511.474.844.84
518.615.155.15
297.752.812.81
463.036.236.23
387.963.903.90
442.513.383.38
356.862.772.77
499.465.095.09
477.936.246.24
416.934.084.08
475.465.365.36
402.934.684.68
329.784.124.12
435.474.694.69
444.464.384.38
326.783.423.42
325.804.034.03
312.762.512.51
281.242.892.89
375.422.582.58
460.894.704.70
486.594.414.41
422.393.243.24
311.823.733.73
443.935.375.37
346.223.653.65
403.552.972.97
414.513.283.28
468.483.693.69
390.413.143.14
361.452.532.53
442.354.724.72
481.906.386.38
422.483.673.67
422.393.123.12
331.754.304.30
372.903.413.41
385.393.463.46
432.474.224.22
364.423.663.66
404.443.583.58
371.913.863.86
329.234.644.64
338.774.034.03
276.773.413.41
348.204.814.81
313.764.164.16
378.863.913.91
286.814.314.31
403.513.273.27
314.864.994.99
450.514.824.82
419.934.954.95
404.463.833.83
436.484.574.57
408.962.822.82
420.945.115.11
423.924.864.86
407.423.703.70
357.772.652.65
269.743.573.57
332.193.463.46
426.883.633.63
392.433.583.58
349.194.214.21
412.974.534.53
367.843.603.60
309.804.334.33
403.552.972.97
260.424.484.48
510.974.684.68
313.764.164.16
422.965.285.28
370.883.213.21
392.433.393.39
331.754.304.30
418.494.904.90
512.504.314.31
355.833.603.60
387.442.932.93
407.443.323.32
316.834.344.34
464.494.964.96
324.312.862.86
382.441.861.86
461.394.584.58
314.753.553.55
420.925.095.09
343.843.533.53
380.902.642.64
444.464.384.38
461.024.154.15
331.754.304.30
365.892.402.40
384.872.752.75
432.474.224.22
507.486.106.10
393.533.953.95
441.525.245.24
511.474.844.84
499.585.345.34
420.924.354.35
339.235.255.25
320.783.893.89
301.804.084.08
398.943.943.94
463.916.246.24
371.914.014.01
417.432.912.91
483.465.215.21
405.934.724.72
423.995.105.10
428.903.283.28
315.834.394.39
366.853.723.72
463.916.246.24
436.484.574.57
451.953.083.08
474.915.135.13
444.513.293.29
438.934.324.32
268.143.663.66
444.464.384.38
445.494.544.54
510.895.415.41
388.873.353.35
406.893.913.91
437.475.605.60
476.524.034.03
454.504.414.41
445.515.155.15
400.432.162.16
405.934.724.72
510.974.684.68
404.403.103.10
295.173.983.98
372.903.563.56
399.933.443.44
360.412.832.83
357.334.014.01
444.464.384.38
351.424.604.60
394.932.582.58
408.893.493.49
432.474.224.22
372.324.404.40
150.181.451.45
401.125.335.33
444.585.245.24
456.533.623.62
404.463.833.83
430.434.074.07
356.783.263.26
407.444.404.40
331.315.425.42
421.464.744.74
243.283.423.42
297.752.812.81
275.784.644.64
474.555.165.16
400.492.672.67
362.433.253.25
319.194.874.87
276.773.563.56
424.015.805.80
418.944.534.53
429.564.854.85
391.523.563.56
296.763.413.41
392.433.583.58
363.775.045.04
301.804.084.08
576.002.542.54
490.554.174.17
471.034.354.35
454.504.414.41
478.836.526.52
388.463.473.47
339.782.512.51
266.134.224.22
378.403.193.19
399.755.325.32
323.323.363.36
443.525.235.23
414.512.982.98
359.863.603.60
419.484.304.30
372.903.613.61
430.455.875.87
496.944.244.24
408.403.283.28
460.894.534.53
288.782.122.12
460.894.534.53
414.504.014.01
397.884.014.01
369.903.823.82
464.494.964.96
387.893.953.95
396.473.733.73
354.334.264.26
392.893.683.68
449.995.195.19
446.504.544.54
381.765.185.18
315.824.394.39
373.884.034.03
347.225.425.42
362.842.912.91
406.363.823.82
401.944.814.81
491.966.806.80
405.453.863.86
435.495.185.18
415.944.694.69
514.934.384.38
407.914.074.07
228.683.393.39
400.954.394.39
444.585.245.24
219.672.822.82
429.465.595.59
330.214.674.67
458.485.405.40
309.333.833.83
399.442.772.77
482.574.304.30
303.772.872.87
394.904.504.50
358.873.023.02
381.884.794.79
458.533.433.43
442.904.394.39
408.453.743.74
237.662.962.96
369.903.823.82
370.482.062.06
209.291.851.85
411.785.195.19
412.455.735.73
414.504.014.01
442.904.394.39
343.863.433.43
443.473.823.82
373.403.163.16
436.485.325.32
448.346.016.01
460.534.854.85
456.533.623.62
275.784.164.16
362.483.233.23
324.792.042.04
420.484.214.21
401.473.233.23
407.904.644.64
361.473.323.32
428.482.992.99
446.905.505.50
413.355.135.13
460.894.534.53
409.954.414.41
456.594.204.20
428.543.683.68
321.303.113.11
315.204.964.96
421.934.784.78
479.476.476.47
439.593.053.05
302.793.483.48
348.415.365.36
401.944.814.81
363.775.045.04
332.743.693.69
392.504.034.03
400.492.672.67
387.964.044.04
405.464.384.38
381.785.255.25
326.783.423.42
336.244.734.73
302.803.283.28
442.394.604.60
417.353.903.90
373.863.523.52
399.974.844.84
452.995.835.83
400.954.344.34
482.485.095.09
460.534.854.85
460.894.534.53
350.183.603.60
363.384.284.28
295.173.983.98
285.804.984.98
442.904.394.39
434.014.104.10
438.964.564.56
380.902.192.19
423.965.785.78
518.615.155.15
384.861.941.94
474.555.165.16
415.503.543.54
377.484.944.94
375.883.763.76
331.204.074.07
380.885.045.04
437.475.605.60
363.894.654.65
309.293.113.11
310.783.723.72
396.493.943.94
295.262.722.72
380.423.393.39
379.912.792.79
463.036.236.23
439.965.235.23
364.372.782.78
385.415.605.60
442.513.383.38
371.844.954.95
425.524.884.88
406.453.823.82
313.764.164.16
412.922.712.71
320.783.893.89
499.585.345.34
470.044.954.95
426.994.924.92
428.924.954.95
375.422.582.58
349.753.613.61
454.954.904.90