Basic Information
ID: ALA1908292
Type: Binding
Description: Inhibition of Pgp expressed in MDR1-MDCKII cells measured by calcein-AM assay
Organism: Canis lupus familiaris
Strain: (null)
Cell type: MDR1-MDCKII
Activity Charts
Bioactivity
Activity Types for Assay ALA1908292
% maximum response
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.41 | 1.78 | 1.78 |
| 290.32 | 1.26 | 1.26 |
| 454.61 | 5.09 | 5.09 |
| 414.53 | 3.37 | 3.37 |
| 259.35 | 2.58 | 2.58 |
| 266.34 | 1.38 | 1.38 |
| 252.35 | 0.60 | 0.60 |
| 444.49 | -0.14 | -0.14 |
| 318.87 | 4.89 | 4.89 |
| 319.88 | 4.81 | 4.81 |
| 234.34 | 2.58 | 2.58 |
| 853.92 | 3.74 | 3.74 |
| 274.80 | 3.82 | 3.82 |
| 733.94 | 1.79 | 1.79 |
| 399.44 | 2.87 | 2.87 |
| 354.45 | 2.65 | 2.65 |
| 670.86 | 3.09 | 3.09 |
| 613.80 | 2.87 | 2.87 |
| 567.80 | 4.75 | 4.75 |
| 505.64 | 2.40 | 2.40 |
| 253.27 | 0.83 | 0.83 |
| 471.69 | 6.45 | 6.45 |
| 295.41 | 1.32 | 1.32 |
| 325.77 | 4.32 | 4.32 |
| 151.25 | 1.91 | 1.91 |
| 295.30 | 2.97 | 2.97 |
| 182.17 | -3.59 | -3.59 |
| 608.69 | 4.17 | 4.17 |
| 454.45 | 0.27 | 0.27 |
| 477.05 | 5.09 | 5.09 |
| 588.56 | 1.34 | 1.34 |
| 810.99 | 3.99 | 3.99 |
| 280.30 | 2.91 | 2.91 |
| 1202.63 | ||
| 480.65 | 4.94 | 4.94 |
| 543.53 | 0.00 | 0.00 |
| 303.20 | 1.94 | 1.94 |
| 504.64 | -0.02 | -0.02 |
| 720.96 | 5.91 | 5.91 |
| 705.65 | 5.58 | 5.58 |
| 382.89 | 4.89 | 4.89 |
| 824.97 | 3.52 | 3.52 |
| 181.22 | 0.57 | 0.57 |
| 452.56 | 4.92 | 4.92 |
| 324.42 | 3.17 | 3.17 |
| 531.44 | 4.21 | 4.21 |
| 527.53 | 1.03 | 1.03 |
| 288.43 | 3.88 | 3.88 |
| 392.47 | 1.90 | 1.90 |
| 563.65 | 5.56 | 5.56 |
| 479.53 | 3.68 | 3.68 |
| 346.34 | 2.18 | 2.18 |
| 382.53 | 3.82 | 3.82 |
| 670.88 | 4.27 | 4.27 |
| 1255.44 | ||
| 471.52 | -0.79 | -0.79 |
| 360.37 | 2.57 | 2.57 |
| 778.95 | 4.75 | 4.75 |
| 747.96 | 2.44 | 2.44 |
| 314.41 | 1.46 | 1.46 |