Basic Information
ID: ALA1908697
Type: Binding
Description: Binding constant for EGFR(L747-E749del, A750P) kinase domain
Activity Charts
Bioactivity
Activity Types for Assay ALA1908697
Kd
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 377.44 | 4.68 | 4.68 |
| 398.48 | 3.33 | 3.33 |
| 401.85 | 3.30 | 3.30 |
| 393.44 | 3.41 | 3.41 |
| 581.07 | 6.14 | 6.14 |
| 475.36 | 4.43 | 4.43 |
| 485.95 | 4.39 | 4.39 |
| 530.46 | 5.19 | 5.19 |
| 380.54 | 3.66 | 3.66 |
| 515.62 | 4.93 | 4.93 |
| 446.91 | 4.28 | 4.28 |
| 493.62 | 4.59 | 4.59 |
| 468.56 | 3.51 | 3.51 |
| 346.82 | 5.01 | 5.01 |
| 527.67 | 5.99 | 5.99 |
| 478.66 | 5.04 | 5.04 |
| 436.27 | 5.49 | 5.49 |
| 562.72 | 5.03 | 5.03 |
| 464.83 | 5.55 | 5.55 |
| 557.05 | 5.93 | 5.93 |
| 370.38 | 3.52 | 3.52 |
| 358.45 | 3.88 | 3.88 |
| 443.36 | 5.77 | 5.77 |
| 441.46 | 1.41 | 1.41 |
| 488.02 | 3.31 | 3.31 |
| 507.57 | 3.50 | 3.50 |
| 312.38 | 1.54 | 1.54 |
| 375.41 | 4.90 | 4.90 |
| 466.54 | 4.35 | 4.35 |
| 346.35 | 2.33 | 2.33 |
| 255.32 | 1.87 | 1.87 |
| 529.53 | 6.36 | 6.36 |
| 476.87 | 5.87 | 5.87 |
| 366.42 | 2.83 | 2.83 |
| 464.60 | 3.50 | 3.50 |
| 641.62 | 6.11 | 6.11 |
| 614.22 | 5.02 | 5.02 |
| 450.51 | 5.22 | 5.22 |
| 470.46 | 3.63 | 3.63 |
| 425.49 | 1.58 | 1.58 |
| 513.65 | 2.15 | 2.15 |
| 437.53 | 3.14 | 3.14 |
| 521.67 | 3.56 | 3.56 |
| 392.44 | 2.54 | 2.54 |
| 532.58 | 3.40 | 3.40 |
| 334.38 | 2.73 | 2.73 |
| 382.25 | 2.45 | 2.45 |
| 539.64 | 3.62 | 3.62 |
| 373.46 | 4.04 | 4.04 |
| 529.57 | 5.11 | 5.11 |
| 518.42 | 6.93 | 6.93 |
| 348.36 | 2.98 | 2.98 |
| 560.68 | 5.86 | 5.86 |
| 439.47 | 3.47 | 3.47 |
| 366.81 | 4.33 | 4.33 |
| 450.35 | 5.04 | 5.04 |
| 570.65 | 5.91 | 5.91 |
| 485.95 | 4.39 | 4.39 |
| 413.83 | 3.88 | 3.88 |
| 632.66 | 5.77 | 5.77 |
| 359.42 | 3.22 | 3.22 |
| 308.35 | 2.84 | 2.84 |
| 524.69 | 4.82 | 4.82 |
| 386.48 | 4.64 | 4.64 |
| 457.69 | 3.53 | 3.53 |
| 442.49 | 1.69 | 1.69 |
| 306.37 | 3.47 | 3.47 |
| 498.66 | 5.26 | 5.26 |
| 543.62 | 5.09 | 5.09 |
| 497.04 | 3.76 | 3.76 |
| 480.55 | 5.39 | 5.39 |
| 332.41 | 2.78 | 2.78 |