ID: ALA1909291
Type: Toxicity
Description: FDA Liver Toxicity Knowledge Base Benchmark Dataset (LTKB-BD) drugs of most concern for DILI
Tissue: Liver
Bioactivity
Activity Types for Assay ALA1909291
LTKB_BD DILI severity score
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
331.35 | 1.58 | 1.58 |
441.55 | 4.37 | 4.37 |
430.38 | 2.88 | 2.88 |
454.61 | 5.09 | 5.09 |
416.36 | 1.89 | 1.89 |
328.41 | 2.14 | 2.14 |
357.35 | 3.56 | 3.56 |
255.32 | 1.53 | 1.53 |
253.28 | 1.37 | 1.37 |
263.38 | 3.83 | 3.83 |
331.18 | 3.75 | 3.75 |
211.22 | 0.44 | 0.44 |
266.30 | 2.65 | 2.65 |
76.05 | -0.96 | -0.96 |
137.14 | -0.31 | -0.31 |
182.19 | 0.07 | 0.07 |
287.22 | -0.05 | -0.05 |
371.52 | 6.00 | 6.00 |
236.30 | 2.73 | 2.73 |
198.27 | 2.70 | 2.70 |
357.79 | 3.93 | 3.93 |
733.94 | 1.79 | 1.79 |
398.48 | 3.33 | 3.33 |
306.28 | 0.74 | 0.74 |
581.07 | 6.14 | 6.14 |
236.27 | 3.39 | 3.39 |
144.21 | 2.29 | 2.29 |
238.33 | 2.85 | 2.85 |
356.42 | 4.37 | 4.37 |
238.16 | 0.07 | 0.07 |
123.11 | 0.78 | 0.78 |
613.80 | 2.87 | 2.87 |
341.41 | 1.53 | 1.53 |
575.69 | 5.70 | 5.70 |
287.36 | 3.38 | 3.38 |
470.02 | 3.55 | 3.55 |
645.32 | 6.94 | 6.94 |
267.24 | -0.20 | -0.20 |
296.15 | 4.36 | 4.36 |
229.26 | -0.59 | -0.59 |
454.45 | 0.27 | 0.27 |
243.22 | -2.56 | -2.56 |
276.21 | 3.21 | 3.21 |
255.75 | 2.55 | 2.55 |
317.23 | 3.84 | 3.84 |
246.31 | -0.28 | -0.28 |
291.44 | 4.88 | 4.88 |
263.79 | 3.96 | 3.96 |
211.22 | -0.50 | -0.50 |
204.31 | -0.29 | -0.29 |
404.34 | 5.50 | 5.50 |
308.31 | 2.76 | 2.76 |
720.96 | 5.91 | 5.91 |
551.63 | 4.20 | 4.20 |
270.21 | 3.25 | 3.25 |
296.55 | 3.62 | 3.62 |
224.22 | -0.71 | -0.71 |
411.47 | 3.42 | 3.42 |
277.50 | 5.30 | 5.30 |
334.17 | 2.89 | 2.89 |
238.24 | 0.96 | 0.96 |
226.66 | 2.53 | 2.53 |
179.22 | 0.72 | 0.72 |
378.43 | 3.52 | 3.52 |
278.22 | 1.15 | 1.15 |
364.41 | 3.57 | 3.57 |
326.44 | 5.17 | 5.17 |
337.46 | 4.50 | 4.50 |
153.14 | 0.67 | 0.67 |
176.18 | 0.60 | 0.60 |
301.73 | 4.34 | 4.34 |
192.26 | 2.51 | 2.51 |
364.44 | 5.30 | 5.30 |
215.23 | -0.37 | -0.37 |
372.81 | 3.14 | 3.14 |
249.27 | 3.60 | 3.60 |
242.27 | 3.67 | 3.67 |
531.44 | 4.21 | 4.21 |
279.38 | 2.98 | 2.98 |
273.24 | 2.55 | 2.55 |
495.75 | 6.88 | 6.88 |
251.71 | 2.90 | 2.90 |
169.57 | 1.77 | 1.77 |
286.34 | 1.09 | 1.09 |
523.55 | 0.66 | 0.66 |
152.18 | 0.64 | 0.64 |
822.95 | 4.34 | 4.34 |
602.68 | 7.33 | 7.33 |
424.09 | 5.46 | 5.46 |
236.23 | -0.21 | -0.21 |
518.09 | 5.14 | 5.14 |
310.47 | 4.63 | 4.63 |
337.46 | 4.22 | 4.22 |
317.34 | 3.38 | 3.38 |
388.85 | 2.79 | 2.79 |
337.57 | 5.56 | 5.56 |
114.17 | 0.71 | 0.71 |
170.24 | 1.38 | 1.38 |
293.73 | 4.16 | 4.16 |
387.85 | 3.46 | 3.46 |
372.09 | -1.27 | -1.27 |
645.61 | -8.56 | -8.56 |
442.48 | 4.56 | 4.56 |
473.57 | 1.10 | 1.10 |
437.53 | 3.14 | 3.14 |
373.37 | 3.71 | 3.71 |
282.30 | 2.55 | 2.55 |
306.45 | 3.54 | 3.54 |
332.48 | 4.40 | 4.40 |
273.74 | 1.62 | 1.62 |
244.25 | -0.05 | -0.05 |
231.25 | 1.42 | 1.42 |
513.68 | 5.95 | 5.95 |
558.52 | 0.90 | 0.90 |
314.26 | 1.74 | 1.74 |
357.35 | 0.99 | 0.99 |
577.72 | 4.58 | 4.58 |
555.66 | 4.26 | 4.26 |
298.35 | 1.02 | 1.02 |
266.30 | 3.93 | 3.93 |
300.83 | 4.87 | 4.87 |
265.22 | -2.89 | -2.89 |
137.19 | 1.30 | 1.30 |
477.44 | 2.05 | 2.05 |
238.08 | 3.01 | 3.01 |
401.96 | 4.53 | 4.53 |
253.71 | 3.09 | 3.09 |
136.20 | 1.21 | 1.21 |
434.52 | 2.76 | 2.76 |
248.20 | 2.00 | 2.00 |
166.22 | 0.92 | 0.92 |
1216.35 | ||
443.46 | 3.76 | 3.76 |
375.42 | 4.71 | 4.71 |
425.39 | -3.85 | -3.85 |
861.94 | 3.26 | 3.26 |