Basic Information
ID: ALA1912843
Type: Binding
Description: Inhibition of 14-3-3sigma binding domain in human Ba/F3 cells expressing imatibib-resistant Bcr-Abl T315I mutant construct assessed as inhibition of 14-3-3sigma-c-Abl interaction
Organism: Homo sapiens
Cell type: BaF3
Activity Charts
Bioactivity
Activity Types for Assay ALA1912843
LD50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 431.40 | 4.68 | 4.68 |
| 395.37 | 2.13 | 2.13 |