Assay Report Card

Basic Information

ID: ALA1912844

Type: Binding

Description: Inhibition of 14-3-3sigma in human Ba/F3 cells expressing imatinib-sensitive wild type Bcr-Abl construct assessed as release of full-length c-Abl from cytoplasmic complex with 14-3-3sigma at 5 uM after 24 hrs by immunoprecipitation/immunoblot technique

Organism: Homo sapiens

Cell type: BaF3

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
431.404.684.68