Inhibition of 14-3-3sigma in human Ba/F3 cells expressing imatinib-sensitive wild type Bcr-Abl construct assessed as nuclear import of full-length c-A...

Basic Information

ID: ALA1912846

Type: Binding

Description: Inhibition of 14-3-3sigma in human Ba/F3 cells expressing imatinib-sensitive wild type Bcr-Abl construct assessed as nuclear import of full-length c-Abl at 5 uM after 24 hrs by immunoprecipitation/immunoblot technique

Format: BAO_0000219

Organism: Homo sapiens

Cell type: BaF3

Target:  14-3-3 protein sigma(ALA1909482)

Document:  ALA1909530

Inhibition of 14-3-3sigma in human Ba/F3 cells expressing imatinib-sensitive wild type Bcr-Abl construct assessed as nuclear import of full-length c-Abl at 5 uM after 24 hrs by immunoprecipitation/immunoblot technique: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
431.404.684.68