Basic Information
ID: ALA1913351
Type: Binding
Description: Inhibition of aggrecanase-1
Format: BAO_0000357
Target: ADAMTS4(ALA2318)
Document: ALA1909576
Inhibition of aggrecanase-1: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1913351
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 349.41 | 2.45 | 2.45 |
| 349.41 | 2.45 | 2.45 |
| 333.41 | 2.74 | 2.74 |
| 493.58 | 5.37 | 5.37 |
| 363.44 | 2.23 | 2.23 |
| 376.43 | 1.84 | 1.84 |
| 390.46 | 2.70 | 2.70 |
| 362.45 | 2.20 | 2.20 |
| 404.49 | 2.38 | 2.38 |
| 358.42 | 2.61 | 2.61 |
| 363.44 | 2.23 | 2.23 |
| 390.46 | 2.70 | 2.70 |
| 406.46 | 2.46 | 2.46 |
| 392.43 | 2.20 | 2.20 |
| 404.49 | 2.38 | 2.38 |
| 418.52 | 2.72 | 2.72 |
| 466.56 | 3.67 | 3.67 |
| 425.51 | 4.53 | 4.53 |
| 439.53 | 4.32 | 4.32 |
| 468.53 | 4.35 | 4.35 |
| 482.56 | 4.03 | 4.03 |
| 489.57 | 3.51 | 3.51 |
| 445.58 | 4.70 | 4.70 |
| 489.59 | 5.47 | 5.47 |
| 489.59 | 5.47 | 5.47 |
| 490.58 | 4.87 | 4.87 |
| 504.61 | 5.18 | 5.18 |
| 490.58 | 4.87 | 4.87 |
| 440.52 | 3.72 | 3.72 |
| 440.52 | 3.72 | 3.72 |
| 440.52 | 3.72 | 3.72 |
| 454.55 | 4.02 | 4.02 |
| 508.52 | 4.73 | 4.73 |
| 508.52 | 4.73 | 4.73 |
| 507.53 | 5.34 | 5.34 |
| 464.54 | 4.19 | 4.19 |
| 464.54 | 4.19 | 4.19 |
| 507.53 | 5.34 | 5.34 |
| 464.54 | 4.19 | 4.19 |
| 507.53 | 5.34 | 5.34 |
| 521.56 | 5.90 | 5.90 |
| 484.53 | 4.23 | 4.23 |
| 457.52 | 4.46 | 4.46 |
| 473.98 | 4.97 | 4.97 |
| 497.57 | 4.11 | 4.11 |
| 483.54 | 4.02 | 4.02 |
| 518.43 | 5.08 | 5.08 |
| 455.53 | 4.03 | 4.03 |