Basic Information
ID: ALA1914006
Type: Binding
Description: Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) assessed as reduction in dephosphorylation of Z'-Lyte phospho-Tyr 1 peptide preincubated for 20 mins by FRET assay
Format: BAO_0000019
Target: Protein-tyrosine phosphatase 1B(ALA335)
Document: ALA1909518
Inhibition of PTP1B expressed in Escherichia coli BL21 (DE3) assessed as reduction in dephosphorylation of Z'-Lyte phospho-Tyr 1 peptide preincubated for 20 mins by FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1914006
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.23 | 5.05 | 5.05 |
| 250.34 | 3.74 | 3.74 |
| 284.79 | 4.39 | 4.39 |
| 284.79 | 4.39 | 4.39 |
| 319.23 | 5.05 | 5.05 |
| 278.40 | 4.36 | 4.36 |
| 300.40 | 4.89 | 4.89 |
| 408.14 | 5.26 | 5.26 |
| 303.17 | 4.33 | 4.33 |
| 302.18 | 4.37 | 4.37 |
| 351.23 | 3.73 | 3.73 |
| 396.34 | 4.04 | 4.04 |
| 458.41 | 5.47 | 5.47 |
| 473.43 | 5.05 | 5.05 |
| 532.45 | 5.17 | 5.17 |
| 546.48 | 5.26 | 5.26 |
| 313.21 | 4.98 | 4.98 |
| 390.31 | 3.98 | 3.98 |
| 392.10 | 5.75 | 5.75 |
| 381.28 | 4.72 | 4.72 |
| 428.34 | 5.97 | 5.97 |
| 485.39 | 5.28 | 5.28 |
| 447.77 | 7.04 | 7.04 |