Assay Report Card

Basic Information

ID: ALA1914011

Type: Binding

Description: Irreversible inhibition of PAD4 assessed as hydrolysis of benzoyl-L-arginine ethyl ester preincubated for 15 mins measured after 15 mins by fluorometric analysis

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
452.360.290.29
468.820.550.55
424.810.860.86
408.350.590.59
112.54-0.11-0.11
154.620.930.93
202.661.721.72
188.632.052.05
456.401.871.87
442.372.002.00
456.401.871.87
470.421.551.55
365.331.731.73
401.381.281.28
444.410.140.14
398.32-0.69-0.69
397.33-0.09-0.09
469.350.200.20