Inhibition of mouse recombinant PI3K p110alpha expressed in Sf21 insect cells using phosphatidylinositol as substrate after 1 hr by phosphoimaging

Basic Information

ID: ALA1914129

Type: Binding

Description: Inhibition of mouse recombinant PI3K p110alpha expressed in Sf21 insect cells using phosphatidylinositol as substrate after 1 hr by phosphoimaging

Format: BAO_0000219

Organism: Mus musculus

Target: PI3-kinase p110-alpha subunit(ALA2499)

Document: ALA1909493

Inhibition of mouse recombinant PI3K p110alpha expressed in Sf21 insect cells using phosphatidylinositol as substrate after 1 hr by phosphoimaging: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA1914129

IC50

Total(42)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
417.42	1.82	1.82
367.41	0.88	0.88
381.44	1.19	1.19
399.43	1.35	1.35
435.41	1.90	1.90
397.44	0.38	0.38
427.53	1.75	1.75
443.53	0.76	0.76
459.53	0.43	0.43
413.51	1.61	1.61
445.51	0.29	0.29
433.42	1.53	1.53
447.45	1.83	1.83
461.47	2.22	2.22
475.50	2.61	2.61
489.53	3.00	3.00
483.43	2.42	2.42
475.50	2.61	2.61
511.51	1.16	1.16
432.44	1.40	1.40
446.46	1.86	1.86
460.49	1.89	1.89
447.45	1.31	1.31
475.46	1.61	1.61
460.45	0.92	0.92
474.47	1.18	1.18
488.50	1.52	1.52
442.43	1.69	1.69
461.43	1.55	1.55
477.47	1.84	1.84
463.45	1.54	1.54
463.45	1.54	1.54
477.47	1.84	1.84
462.46	1.41	1.41
476.49	1.87	1.87
490.52	1.90	1.90
448.43	1.22	1.22
416.43	2.43	2.43
432.43	2.13	2.13
446.46	2.43	2.43
416.43	2.43	2.43
446.46	2.43	2.43