Basic Information
ID: ALA1918739
Type: ADME
Description: Selectivity ratio of EC50 for human HepG2 cells to EC50 for Plasmodium falciparum
Format: BAO_0000219
Cell type: HepG2
Target: ADMET(ALA612558)
Document: ALA1914304
Selectivity ratio of EC50 for human HepG2 cells to EC50 for Plasmodium falciparum: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1918739
Ratio EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 472.00 | 4.56 | 4.56 |
| 409.93 | 3.72 | 3.72 |
| 437.98 | 4.50 | 4.50 |
| 466.04 | 5.28 | 5.28 |
| 472.00 | 5.30 | 5.30 |
| 518.11 | 6.35 | 6.35 |
| 443.95 | 4.17 | 4.17 |
| 520.04 | 6.09 | 6.09 |
| 520.04 | 6.53 | 6.53 |
| 536.04 | 6.23 | 6.23 |
| 472.00 | 4.56 | 4.56 |
| 409.93 | 3.72 | 3.72 |
| 437.98 | 4.50 | 4.50 |
| 466.04 | 5.28 | 5.28 |
| 518.11 | 6.35 | 6.35 |
| 461.94 | 4.31 | 4.31 |
| 538.03 | 6.23 | 6.23 |
| 538.03 | 6.67 | 6.67 |
| 554.03 | 6.37 | 6.37 |
| 489.99 | 4.69 | 4.69 |
| 427.92 | 3.86 | 3.86 |
| 455.97 | 4.64 | 4.64 |
| 484.03 | 5.42 | 5.42 |
| 489.99 | 5.44 | 5.44 |
| 536.10 | 6.49 | 6.49 |
| 403.95 | 3.73 | 3.73 |
| 480.05 | 5.12 | 5.12 |
| 494.08 | 5.20 | 5.20 |
| 514.49 | 5.77 | 5.77 |
| 510.07 | 4.31 | 4.31 |
| 530.49 | 4.88 | 4.88 |
| 481.04 | 4.06 | 4.06 |
| 495.06 | 4.06 | 4.06 |
| 495.06 | 4.37 | 4.37 |
| 495.06 | 4.37 | 4.37 |
| 495.06 | 4.37 | 4.37 |
| 511.06 | 4.07 | 4.07 |
| 511.06 | 4.07 | 4.07 |
| 511.06 | 4.07 | 4.07 |
| 515.48 | 4.72 | 4.72 |
| 515.48 | 4.72 | 4.72 |
| 549.93 | 5.37 | 5.37 |
| 499.03 | 4.20 | 4.20 |
| 499.03 | 4.20 | 4.20 |
| 526.03 | 3.97 | 3.97 |
| 496.05 | 3.65 | 3.65 |
| 497.04 | 3.77 | 3.77 |
| 549.03 | 5.08 | 5.08 |
| 509.05 | 3.70 | 3.70 |
| 418.97 | 2.49 | 2.49 |
| 571.16 | 5.65 | 5.65 |
| 432.99 | 2.88 | 2.88 |
| 405.92 | 2.57 | 2.57 |
| 589.15 | 6.34 | 6.34 |
| 421.94 | 3.87 | 3.87 |
| 498.04 | 5.26 | 5.26 |
| 512.07 | 5.34 | 5.34 |
| 532.48 | 5.91 | 5.91 |
| 528.06 | 4.45 | 4.45 |
| 548.48 | 5.02 | 5.02 |
| 499.03 | 4.20 | 4.20 |
| 513.05 | 4.20 | 4.20 |
| 513.05 | 4.51 | 4.51 |
| 513.05 | 4.51 | 4.51 |
| 513.05 | 4.51 | 4.51 |
| 529.05 | 4.21 | 4.21 |
| 529.05 | 4.21 | 4.21 |
| 529.05 | 4.21 | 4.21 |
| 533.47 | 4.86 | 4.86 |
| 533.47 | 4.86 | 4.86 |
| 567.92 | 5.51 | 5.51 |
| 517.02 | 4.34 | 4.34 |
| 517.02 | 4.34 | 4.34 |
| 544.02 | 4.11 | 4.11 |
| 514.04 | 3.79 | 3.79 |
| 515.03 | 3.91 | 3.91 |
| 567.02 | 5.22 | 5.22 |
| 527.04 | 3.84 | 3.84 |
| 436.96 | 2.63 | 2.63 |
| 589.15 | 5.79 | 5.79 |
| 450.98 | 3.02 | 3.02 |
| 423.91 | 2.71 | 2.71 |
| 512.07 | 5.34 | 5.34 |
| 528.06 | 4.45 | 4.45 |
| 422.93 | 2.29 | 2.29 |
| 498.04 | 5.26 | 5.26 |
| 533.47 | 4.86 | 4.86 |
| 499.03 | 4.20 | 4.20 |
| 513.05 | 4.20 | 4.20 |
| 513.05 | 4.51 | 4.51 |
| 513.05 | 4.51 | 4.51 |
| 513.05 | 4.51 | 4.51 |
| 529.05 | 4.21 | 4.21 |
| 529.05 | 4.21 | 4.21 |
| 529.05 | 4.21 | 4.21 |
| 533.47 | 4.86 | 4.86 |
| 567.92 | 5.51 | 5.51 |
| 517.02 | 4.34 | 4.34 |
| 517.02 | 4.34 | 4.34 |
| 549.47 | 4.86 | 4.86 |