Therapeutic index, ratio of IC50 for human ERG expressed in CHO cells to EC50 for chloroquine-resistant Plasmodium falciparum K1

Basic Information

ID: ALA1918929

Type: ADME

Description: Therapeutic index, ratio of IC50 for human ERG expressed in CHO cells to EC50 for chloroquine-resistant Plasmodium falciparum K1

Format: BAO_0000219

Cell type: CHO

Target:  ADMET(ALA612558)

Document:  ALA1914304

Therapeutic index, ratio of IC50 for human ERG expressed in CHO cells to EC50 for chloroquine-resistant Plasmodium falciparum K1: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
341.453.243.24
480.055.125.12
495.064.374.37
571.165.655.65
589.155.795.79