Basic Information
ID: ALA1918958
Type: Binding
Description: Inhibition of N-terminal His-tagged human PDE10A expressed in Escherichia coli using [3H]cAMP after 1 hr by scintillation proximity assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1918958
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 326.83 | 3.72 | 3.72 |
| 270.34 | 2.86 | 2.86 |
| 318.38 | 3.88 | 3.88 |
| 372.35 | 4.59 | 4.59 |
| 338.80 | 4.22 | 4.22 |
| 373.24 | 4.88 | 4.88 |
| 356.79 | 4.36 | 4.36 |
| 334.38 | 3.58 | 3.58 |
| 388.35 | 4.47 | 4.47 |
| 347.38 | 2.67 | 2.67 |
| 347.38 | 2.67 | 2.67 |
| 372.35 | 4.59 | 4.59 |
| 392.77 | 4.93 | 4.93 |
| 427.21 | 5.59 | 5.59 |
| 410.76 | 5.07 | 5.07 |
| 410.76 | 5.07 | 5.07 |
| 422.79 | 4.94 | 4.94 |
| 392.77 | 4.93 | 4.93 |
| 374.78 | 4.85 | 4.85 |
| 349.78 | 3.79 | 3.79 |
| 324.41 | 3.94 | 3.94 |
| 307.36 | 2.91 | 2.91 |
| 294.32 | 2.29 | 2.29 |
| 322.37 | 2.91 | 2.91 |
| 336.40 | 2.92 | 2.92 |
| 323.36 | 3.17 | 3.17 |
| 339.42 | 3.64 | 3.64 |
| 306.33 | 2.36 | 2.36 |
| 305.34 | 2.96 | 2.96 |
| 319.37 | 3.27 | 3.27 |
| 319.37 | 3.27 | 3.27 |
| 319.37 | 3.27 | 3.27 |
| 339.79 | 3.62 | 3.62 |
| 319.37 | 3.27 | 3.27 |
| 339.79 | 3.62 | 3.62 |
| 335.37 | 2.97 | 2.97 |
| 335.37 | 2.97 | 2.97 |
| 288.35 | 3.87 | 3.87 |
| 306.34 | 4.01 | 4.01 |
| 306.34 | 4.01 | 4.01 |
| 305.36 | 4.61 | 4.61 |
| 322.80 | 4.52 | 4.52 |
| 322.80 | 4.52 | 4.52 |
| 318.38 | 3.88 | 3.88 |
| 372.35 | 4.77 | 4.77 |
| 372.35 | 4.77 | 4.77 |
| 356.35 | 4.89 | 4.89 |
| 356.35 | 4.89 | 4.89 |
| 356.35 | 4.89 | 4.89 |
| 324.33 | 4.15 | 4.15 |
| 324.33 | 4.15 | 4.15 |
| 336.37 | 4.02 | 4.02 |
| 336.37 | 4.02 | 4.02 |
| 336.37 | 4.02 | 4.02 |
| 356.43 | 4.39 | 4.39 |
| 353.40 | 3.66 | 3.66 |
| 335.38 | 4.62 | 4.62 |
| 371.36 | 5.22 | 5.22 |
| 349.41 | 5.01 | 5.01 |
| 403.38 | 5.55 | 5.55 |
| 375.45 | 5.40 | 5.40 |
| 321.36 | 4.32 | 4.32 |
| 348.41 | 3.89 | 3.89 |
| 348.41 | 3.89 | 3.89 |
| 348.41 | 3.89 | 3.89 |
| 403.49 | 3.71 | 3.71 |
| 403.49 | 3.71 | 3.71 |
| 424.50 | 5.46 | 5.46 |
| 384.39 | 4.48 | 4.48 |
| 386.38 | 4.90 | 4.90 |
| 352.83 | 4.53 | 4.53 |
| 390.80 | 5.54 | 5.54 |
| 336.37 | 4.02 | 4.02 |
| 336.37 | 4.02 | 4.02 |
| 336.37 | 4.02 | 4.02 |
| 372.35 | 4.61 | 4.61 |
| 404.37 | 4.95 | 4.95 |
| 376.44 | 4.80 | 4.80 |
| 353.40 | 3.66 | 3.66 |