Basic Information
ID: ALA1919134
Type: Binding
Description: Ratio of compound IC50 to n-heptyl alpha-D-mannopyranoside IC50 for Escherichia coli recombinant C-terminal 6His-tagged FimH-CRD with a C-terminal thrombin cleavage site expressed in Escherichia coli HM125 assessed as inhibition of streptavidin-horseradish peroxidase conjugated TM-PAA polymer binding after 3 hrs by spectrophotometry
Organism: Escherichia coli
Activity Charts
Bioactivity
Activity Types for Assay ALA1919134
Ratio IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 194.18 | -2.57 | -2.57 |
| 337.33 | -1.17 | -1.17 |
| 403.32 | -1.72 | -1.72 |
| 403.32 | -1.72 | -1.72 |
| 404.31 | -2.32 | -2.32 |
| 351.36 | -1.36 | -1.36 |
| 352.35 | -1.83 | -1.83 |
| 395.46 | -0.48 | -0.48 |
| 381.39 | -1.35 | -1.35 |
| 381.39 | -1.35 | -1.35 |
| 382.33 | -1.51 | -1.51 |
| 338.32 | -2.02 | -2.02 |
| 355.32 | -1.28 | -1.28 |
| 355.32 | -1.28 | -1.28 |
| 367.36 | -1.41 | -1.41 |
| 395.41 | -1.31 | -1.31 |
| 396.36 | -1.47 | -1.47 |
| 352.35 | -1.98 | -1.98 |
| 369.35 | -1.23 | -1.23 |
| 307.31 | -1.08 | -1.08 |
| 321.33 | -0.77 | -0.77 |
| 341.75 | -0.43 | -0.43 |
| 375.30 | -0.06 | -0.06 |
| 308.29 | -1.69 | -1.69 |
| 321.33 | -1.21 | -1.21 |
| 335.36 | -0.90 | -0.90 |
| 355.78 | -0.56 | -0.56 |
| 389.33 | -0.19 | -0.19 |
| 322.32 | -1.82 | -1.82 |
| 351.36 | -1.30 | -1.30 |