Basic Information
ID: ALA1919337
Type: Functional
Description: Antagonist activity at human FPR1 in human neutrophils assessed as inhibition of fMLF-stimulated intracellular calcium mobilisation by FLIPR assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1919337
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 423.54 | 5.24 | 5.24 |
| 394.50 | 4.49 | 4.49 |
| 426.54 | 3.90 | 3.90 |
| 438.55 | 4.04 | 4.04 |
| 452.58 | 4.39 | 4.39 |
| 446.53 | 3.91 | 3.91 |
| 474.59 | 4.53 | 4.53 |
| 440.57 | 4.29 | 4.29 |
| 440.53 | 2.89 | 2.89 |
| 426.54 | 3.90 | 3.90 |
| 412.52 | 3.59 | 3.59 |
| 404.54 | 3.48 | 3.48 |
| 427.53 | 3.29 | 3.29 |
| 426.54 | 3.90 | 3.90 |
| 426.54 | 3.90 | 3.90 |
| 460.99 | 4.55 | 4.55 |
| 451.55 | 3.77 | 3.77 |
| 427.53 | 3.29 | 3.29 |
| 440.57 | 3.96 | 3.96 |
| 392.53 | 3.49 | 3.49 |
| 479.56 | 4.25 | 4.25 |
| 519.63 | 5.12 | 5.12 |
| 440.57 | 4.21 | 4.21 |
| 412.52 | 3.43 | 3.43 |
| 452.58 | 4.35 | 4.35 |
| 466.61 | 4.69 | 4.69 |
| 452.58 | 4.29 | 4.29 |
| 466.61 | 4.60 | 4.60 |
| 454.55 | 3.20 | 3.20 |
| 440.57 | 4.07 | 4.07 |
| 426.54 | 3.82 | 3.82 |
| 454.60 | 4.45 | 4.45 |
| 454.60 | 4.45 | 4.45 |
| 454.60 | 4.45 | 4.45 |
| 508.57 | 5.16 | 5.16 |
| 446.62 | 4.42 | 4.42 |
| 459.55 | 3.68 | 3.68 |
| 483.57 | 4.16 | 4.16 |
| 526.56 | 5.30 | 5.30 |