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Inhibition of CYP3A4/5-mediated midazolam 1'-hydroxylation in human liver microsomes by LCMS analysis

Basic Information

ID: ALA1919561

Type: ADME

Description: Inhibition of CYP3A4/5-mediated midazolam 1'-hydroxylation in human liver microsomes by LCMS analysis

Format: BAO_0000251

Organism: Homo sapiens

Tissue: Liver

Subcellular Fraction: Microsome

Target:  Cytochrome P450 3A4/3A5(ALA2111472)

Document:  ALA1914447

Inhibition of CYP3A4/5-mediated midazolam 1'-hydroxylation in human liver microsomes by LCMS analysis: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA1919561

IC50

Total(1)

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
369.493.403.40
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