Basic Information
ID: ALA1921086
Type: Functional
Description: Agonist activity at FXR in human HepG2 cells assessed as inhibition of CYP7A1 mRNA expression at 50 uM for 6 hrs by RT-PCR relative to control
Organism: Homo sapiens
Cell type: HepG2
Activity Charts
Bioactivity
Activity Types for Assay ALA1921086
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 428.66 | 6.47 | 6.47 |
| 392.58 | 4.48 | 4.48 |
| 468.68 | 6.50 | 6.50 |
| 454.70 | 6.41 | 6.41 |
| 472.71 | 5.60 | 5.60 |
| 472.71 | 6.03 | 6.03 |