Assay Report Card

Basic Information

ID: ALA1921088

Type: Functional

Description: Antiinflammatory activity in human HUVEC cells assessed as inhibition of TNF-alpha-induced IL-8 mRNA expression at 5 uM for 10 mins measured after 4 hrs of LPS challenge by Q-PCR analysis

Organism: Homo sapiens

Cell type: HUVEC

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
428.666.476.47
468.686.506.50
454.706.416.41
472.715.605.60
472.716.036.03