Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by rad...

Basic Information

ID: ALA1921531

Type: Binding

Description: Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by radio flow detector-based HPLC analysis in presence of NAD+ as cofactor

Format: BAO_0000019

Organism: Homo sapiens

Target: Estradiol 17-beta-dehydrogenase 2(ALA2789)

Document: ALA1914317

Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by radio flow detector-based HPLC analysis in presence of NAD+ as cofactor: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA1921531

IC50

Total(26)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
361.44	4.64	4.64
333.39	4.04	4.04
345.44	4.94	4.94
331.42	4.64	4.64
333.39	4.04	4.04
333.39	4.04	4.04
367.47	4.70	4.70
339.42	4.10	4.10
367.47	4.70	4.70
339.42	4.10	4.10
339.42	4.10	4.10
323.42	4.39	4.39
337.44	4.70	4.70
337.44	4.70	4.70
337.44	4.70	4.70
323.42	4.39	4.39
348.43	4.26	4.26
353.44	4.40	4.40
353.44	4.40	4.40
366.49	4.46	4.46
337.44	4.70	4.70
341.41	4.53	4.53
341.41	4.53	4.53
371.43	4.54	4.54
357.41	4.24	4.24
364.47	3.86	3.86