Basic Information
ID: ALA1921531
Type: Binding
Description: Inhibition of human placental 17beta-HSD2 assessed as formation of [2,4,6,7-3H]-estrone using [2,4,6,7-3H]-estradiol as substrate after 20 mins by radio flow detector-based HPLC analysis in presence of NAD+ as cofactor
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1921531
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 361.44 | 4.64 | 4.64 |
| 333.39 | 4.04 | 4.04 |
| 345.44 | 4.94 | 4.94 |
| 331.42 | 4.64 | 4.64 |
| 333.39 | 4.04 | 4.04 |
| 333.39 | 4.04 | 4.04 |
| 367.47 | 4.70 | 4.70 |
| 339.42 | 4.10 | 4.10 |
| 367.47 | 4.70 | 4.70 |
| 339.42 | 4.10 | 4.10 |
| 339.42 | 4.10 | 4.10 |
| 323.42 | 4.39 | 4.39 |
| 337.44 | 4.70 | 4.70 |
| 337.44 | 4.70 | 4.70 |
| 337.44 | 4.70 | 4.70 |
| 323.42 | 4.39 | 4.39 |
| 348.43 | 4.26 | 4.26 |
| 353.44 | 4.40 | 4.40 |
| 353.44 | 4.40 | 4.40 |
| 366.49 | 4.46 | 4.46 |
| 337.44 | 4.70 | 4.70 |
| 341.41 | 4.53 | 4.53 |
| 341.41 | 4.53 | 4.53 |
| 371.43 | 4.54 | 4.54 |
| 357.41 | 4.24 | 4.24 |
| 364.47 | 3.86 | 3.86 |