Assay Report Card

Basic Information

ID: ALA1921592

Type: Binding

Description: Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA template-primer and nucleotide substrate at 10 uM after 60 mins

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
282.476.116.11
278.445.665.66
280.455.885.88
60.050.090.09
116.161.651.65
74.080.480.48
174.161.331.33
284.486.336.33
200.323.993.99
328.506.556.55
216.191.551.55
302.465.995.99
230.221.941.94
272.303.113.11
356.465.455.45
440.627.797.79
438.617.567.56
436.597.347.34
434.587.127.12
458.607.457.45
484.648.018.01