Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release treated for 5 mins before LPS challenge measured after ...

Basic Information

ID: ALA1924374

Type: Functional

Description: Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release treated for 5 mins before LPS challenge measured after 4 hrs by ELISA

Format: BAO_0000219

Organism: Homo sapiens

Cell type: PBMC

Target: PBMC(ALA613107)

Document: ALA1921674

Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release treated for 5 mins before LPS challenge measured after 4 hrs by ELISA: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA1924374

IC50

Total(28)

Compound Summary

Parent Molecular Weight	ALogP	Polar Surface Area
348.41	2.79	2.79
392.46	2.81	2.81
394.50	3.87	3.87
366.45	3.02	3.02
349.40	2.19	2.19
363.43	2.75	2.75
375.44	2.68	2.68
363.43	2.53	2.53
363.43	2.58	2.58
391.48	3.22	3.22
375.44	2.58	2.58
389.46	2.97	2.97
391.48	3.22	3.22
413.45	2.27	2.27
419.47	2.33	2.33
379.42	1.82	1.82
393.45	2.21	2.21
365.40	1.16	1.16
393.45	1.94	1.94
378.44	1.39	1.39
406.49	2.12	2.12
393.45	2.16	2.16
378.44	2.32	2.32
335.37	2.51	2.51
351.41	2.61	2.61
365.44	2.64	2.64
376.47	2.31	2.31