Basic Information
ID: ALA1924374
Type: Functional
Description: Antiinflammatory activity in human PBMC assessed as inhibition of LPS-induced TNFalpha release treated for 5 mins before LPS challenge measured after 4 hrs by ELISA
Organism: Homo sapiens
Cell type: PBMC
Activity Charts
Bioactivity
Activity Types for Assay ALA1924374
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.41 | 2.79 | 2.79 |
| 392.46 | 2.81 | 2.81 |
| 394.50 | 3.87 | 3.87 |
| 366.45 | 3.02 | 3.02 |
| 349.40 | 2.19 | 2.19 |
| 363.43 | 2.75 | 2.75 |
| 375.44 | 2.68 | 2.68 |
| 363.43 | 2.53 | 2.53 |
| 363.43 | 2.58 | 2.58 |
| 391.48 | 3.22 | 3.22 |
| 375.44 | 2.58 | 2.58 |
| 389.46 | 2.97 | 2.97 |
| 391.48 | 3.22 | 3.22 |
| 413.45 | 2.27 | 2.27 |
| 419.47 | 2.33 | 2.33 |
| 379.42 | 1.82 | 1.82 |
| 393.45 | 2.21 | 2.21 |
| 365.40 | 1.16 | 1.16 |
| 393.45 | 1.94 | 1.94 |
| 378.44 | 1.39 | 1.39 |
| 406.49 | 2.12 | 2.12 |
| 393.45 | 2.16 | 2.16 |
| 378.44 | 2.32 | 2.32 |
| 335.37 | 2.51 | 2.51 |
| 351.41 | 2.61 | 2.61 |
| 365.44 | 2.64 | 2.64 |
| 376.47 | 2.31 | 2.31 |