Basic Information
ID: ALA1924521
Type: Binding
Description: Inhibition of FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 15 mins by ELISA
Organism: Homo sapiens
Tissue: Blood
Activity Charts
Bioactivity
Activity Types for Assay ALA1924521
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 236.30 | 2.73 | 2.73 |
| 472.09 | 8.01 | 8.01 |
| 609.17 | 9.01 | 9.01 |
| 609.79 | 8.28 | 8.28 |
| 624.81 | 7.98 | 7.98 |
| 659.85 | 9.43 | 9.43 |
| 660.84 | 8.83 | 8.83 |
| 677.84 | 9.57 | 9.57 |
| 677.84 | 9.57 | 9.57 |
| 673.88 | 9.74 | 9.74 |
| 648.83 | 8.53 | 8.53 |
| 647.84 | 9.36 | 9.36 |
| 623.82 | 8.59 | 8.59 |
| 623.82 | 8.59 | 8.59 |
| 623.82 | 8.59 | 8.59 |
| 623.82 | 8.59 | 8.59 |
| 637.85 | 8.84 | 8.84 |
| 637.85 | 8.89 | 8.89 |
| 637.85 | 8.89 | 8.89 |
| 644.24 | 8.93 | 8.93 |
| 639.82 | 8.29 | 8.29 |
| 652.82 | 7.38 | 7.38 |
| 624.81 | 7.98 | 7.98 |
| 613.78 | 8.18 | 8.18 |
| 626.82 | 7.93 | 7.93 |
| 626.82 | 7.93 | 7.93 |
| 623.82 | 8.59 | 8.59 |
| 623.82 | 8.59 | 8.59 |
| 661.79 | 9.60 | 9.60 |
| 643.88 | 9.04 | 9.04 |
| 661.79 | 9.60 | 9.60 |
| 661.79 | 9.60 | 9.60 |
| 661.79 | 9.60 | 9.60 |
| 637.85 | 8.98 | 8.98 |
| 637.85 | 8.98 | 8.98 |
| 607.82 | 8.89 | 8.89 |
| 611.78 | 8.72 | 8.72 |
| 611.78 | 8.72 | 8.72 |
| 593.79 | 8.58 | 8.58 |
| 593.79 | 8.58 | 8.58 |
| 609.79 | 7.87 | 7.87 |
| 653.85 | 8.22 | 8.22 |
| 549.67 | 7.09 | 7.09 |
| 653.85 | 7.99 | 7.99 |
| 647.82 | 8.70 | 8.70 |
| 667.81 | 8.51 | 8.51 |