ID: ALA1924522
Type: Binding
Description: Inhibition of FLAP in human whole blood assessed as inhibition of calcium ionophore A23187-induced LTB4 production preincubated for 5 hrs by ELISA
Organism: Homo sapiens
Tissue: Blood
Bioactivity
Activity Types for Assay ALA1924522
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
236.30 | 2.73 | 2.73 |
472.09 | 8.01 | 8.01 |
609.17 | 9.01 | 9.01 |
609.79 | 8.28 | 8.28 |
624.81 | 7.98 | 7.98 |
659.85 | 9.43 | 9.43 |
660.84 | 8.83 | 8.83 |
677.84 | 9.57 | 9.57 |
677.84 | 9.57 | 9.57 |
673.88 | 9.74 | 9.74 |
648.83 | 8.53 | 8.53 |
647.84 | 9.36 | 9.36 |
623.82 | 8.59 | 8.59 |
623.82 | 8.59 | 8.59 |
623.82 | 8.59 | 8.59 |
623.82 | 8.59 | 8.59 |
637.85 | 8.84 | 8.84 |
637.85 | 8.89 | 8.89 |
637.85 | 8.89 | 8.89 |
644.24 | 8.93 | 8.93 |
639.82 | 8.29 | 8.29 |
652.82 | 7.38 | 7.38 |
624.81 | 7.98 | 7.98 |
613.78 | 8.18 | 8.18 |
626.82 | 7.93 | 7.93 |
626.82 | 7.93 | 7.93 |
623.82 | 8.59 | 8.59 |
623.82 | 8.59 | 8.59 |
661.79 | 9.60 | 9.60 |
643.88 | 9.04 | 9.04 |
661.79 | 9.60 | 9.60 |
661.79 | 9.60 | 9.60 |
661.79 | 9.60 | 9.60 |
637.85 | 8.98 | 8.98 |
637.85 | 8.98 | 8.98 |
607.82 | 8.89 | 8.89 |
611.78 | 8.72 | 8.72 |
611.78 | 8.72 | 8.72 |
593.79 | 8.58 | 8.58 |
593.79 | 8.58 | 8.58 |
609.79 | 7.87 | 7.87 |
653.85 | 8.22 | 8.22 |
549.67 | 7.09 | 7.09 |
653.85 | 7.99 | 7.99 |
647.82 | 8.70 | 8.70 |
667.81 | 8.51 | 8.51 |