Assay Report Card

Basic Information

ID: ALA1925814

Type: Binding

Description: Stabilization of Escherichia coli DNA topoisomerase 1-DNA cleavage complex assessed as cleavage enhancement using 32P-TAACCCTGAAAGATTATGCAATGCGCTTTGGG ssDNA as substrate at 10 to 200 uM at pH 8 after 20 mins by agarose gel electrophoresis relative to control

Organism: Escherichia coli

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
265.271.641.64