Basic Information
ID: ALA1932144
Type: Functional
Description: Antiplasmodial activity against chloroquine-resistant Plasmodium falciparum FcB1/Colombia infected in human A+ve erythrocytes assessed as inhibition of [G-3H]hypoxanthine uptake preincubated for 24 hrs prior to [G-3H]hypoxanthine addition measured after 18 hrs by liquid scintillation counting
Organism: Plasmodium falciparum
Strain: FcB1/Columbia
Activity Charts
Bioactivity
Activity Types for Assay ALA1932144
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 340.43 | 2.88 | 2.88 |
| 348.36 | 2.08 | 2.08 |
| 319.88 | 4.81 | 4.81 |
| 228.25 | 2.98 | 2.98 |
| 323.35 | 3.29 | 3.29 |
| 230.26 | 3.01 | 3.01 |
| 173.60 | -1.13 | -1.13 |
| 428.42 | ||
| 572.56 | -2.11 | -2.11 |
| 483.47 | -2.43 | -2.43 |
| 422.43 | 0.46 | 0.46 |
| 244.29 | 3.31 | 3.31 |
| 500.45 | -2.17 | -2.17 |
| 301.30 | 2.12 | 2.12 |
| 498.57 | 4.29 | 4.29 |