Basic Information
ID: ALA1936279
Type: Binding
Description: Inhibition of mPGES-1 in human A549 cell microsomes assessed as conversion of PGH2 into PGE2 at 3.3 uM at 0 degC after 5 mins by HPLC-UV analysis
Organism: Homo sapiens
Cell type: A549
Subcellular Fraction: Microsome
Activity Charts
Bioactivity
Activity Types for Assay ALA1936279
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 447.70 | 8.10 | 8.10 |
| 363.54 | 5.76 | 5.76 |
| 251.33 | 2.64 | 2.64 |
| 293.41 | 3.81 | 3.81 |
| 307.43 | 4.20 | 4.20 |
| 335.49 | 4.98 | 4.98 |
| 391.60 | 6.54 | 6.54 |
| 419.65 | 7.32 | 7.32 |
| 413.56 | 5.63 | 5.63 |
| 399.53 | 5.24 | 5.24 |
| 385.50 | 4.85 | 4.85 |
| 285.34 | 2.89 | 2.89 |
| 335.40 | 4.04 | 4.04 |
| 335.40 | 4.04 | 4.04 |
| 313.40 | 3.47 | 3.47 |
| 361.44 | 4.56 | 4.56 |
| 375.47 | 4.75 | 4.75 |