Basic Information
ID: ALA1936799
Type: Binding
Description: Inhibition of human BCRP expressed in MDCK2 cells assessed as Hoechst 33342 accumulation preincubated for 30 mins by fluorimetry
Organism: Homo sapiens
Cell type: MDCK-II
Activity Charts
Bioactivity
Activity Types for Assay ALA1936799
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 268.31 | 3.60 | 3.60 |
| 224.26 | 3.29 | 3.29 |
| 298.34 | 3.61 | 3.61 |
| 298.34 | 3.61 | 3.61 |
| 240.26 | 2.99 | 2.99 |
| 254.28 | 3.30 | 3.30 |
| 274.70 | 3.65 | 3.65 |
| 302.76 | 4.25 | 4.25 |
| 270.28 | 3.00 | 3.00 |
| 284.31 | 3.31 | 3.31 |
| 254.28 | 3.30 | 3.30 |
| 284.31 | 3.31 | 3.31 |
| 314.34 | 3.31 | 3.31 |
| 344.36 | 3.32 | 3.32 |
| 302.76 | 4.25 | 4.25 |
| 318.76 | 3.96 | 3.96 |
| 314.34 | 3.31 | 3.31 |
| 284.31 | 3.31 | 3.31 |
| 288.73 | 3.95 | 3.95 |
| 288.73 | 3.95 | 3.95 |
| 469.58 | 3.64 | 3.64 |
| 242.71 | 4.24 | 4.24 |
| 270.28 | 3.00 | 3.00 |
| 300.31 | 3.01 | 3.01 |
| 328.36 | 3.62 | 3.62 |
| 274.70 | 3.65 | 3.65 |
| 323.17 | 4.60 | 4.60 |
| 328.36 | 3.62 | 3.62 |
| 339.17 | 4.75 | 4.75 |
| 302.76 | 4.25 | 4.25 |
| 302.76 | 4.25 | 4.25 |
| 274.32 | 4.44 | 4.44 |
| 304.35 | 4.45 | 4.45 |
| 334.37 | 4.46 | 4.46 |
| 304.35 | 4.45 | 4.45 |
| 308.76 | 5.09 | 5.09 |
| 308.76 | 5.09 | 5.09 |
| 343.21 | 5.75 | 5.75 |
| 274.32 | 4.44 | 4.44 |
| 304.35 | 4.45 | 4.45 |
| 334.37 | 4.46 | 4.46 |
| 304.35 | 4.45 | 4.45 |
| 308.76 | 5.09 | 5.09 |
| 308.76 | 5.09 | 5.09 |
| 343.21 | 5.75 | 5.75 |