Basic Information
ID: ALA1936831
Type: Functional
Description: Inhibition of human recombinant MMP12-induced lung inflammation in C57BL/6 mouse assessed as reduction in bronchoalveolar lavage inflammation at 5 mg/kg, po bid at 2 hrs prior to and 12 hrs post challenge measured 24 hrs after last challenge relative to vehicle treated control
Organism: Mus musculus
Strain: C57BL/6
Tissue: Lung
Activity Charts
Bioactivity
Activity Types for Assay ALA1936831
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 430.51 | 4.10 | 4.10 |