Basic Information
ID: ALA1936847
Type: Binding
Description: Inhibition of recombinant perforin-mediated lysis of Jurkat cells assessed as [51Cr] release preincubated with perforin for 30 mins followed by incubation with [51Cr]-labeled Jurkat cells by gamma counting
Cell type: Jurkat
Activity Charts
Bioactivity
Activity Types for Assay ALA1936847
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 326.33 | 1.96 | 1.96 |
| 342.40 | 2.43 | 2.43 |
| 342.40 | 2.43 | 2.43 |
| 336.37 | 2.37 | 2.37 |
| 336.37 | 2.37 | 2.37 |
| 336.37 | 2.37 | 2.37 |
| 337.36 | 1.76 | 1.76 |
| 337.36 | 1.76 | 1.76 |
| 325.35 | 1.70 | 1.70 |
| 327.32 | 1.36 | 1.36 |
| 343.39 | 1.83 | 1.83 |
| 343.39 | 1.83 | 1.83 |
| 343.39 | 1.83 | 1.83 |
| 327.32 | 1.36 | 1.36 |
| 343.39 | 1.83 | 1.83 |
| 343.39 | 1.83 | 1.83 |
| 392.46 | 3.58 | 3.58 |
| 392.46 | 3.58 | 3.58 |
| 392.46 | 3.58 | 3.58 |
| 376.39 | 3.12 | 3.12 |
| 375.41 | 2.85 | 2.85 |
| 375.41 | 2.85 | 2.85 |
| 387.42 | 2.92 | 2.92 |
| 387.42 | 2.92 | 2.92 |
| 331.35 | 0.37 | 0.37 |
| 216.26 | 3.09 | 3.09 |
| 258.30 | 3.29 | 3.29 |
| 244.27 | 2.90 | 2.90 |
| 274.30 | 2.71 | 2.71 |
| 288.32 | 2.80 | 2.80 |
| 326.33 | 2.27 | 2.27 |
| 359.45 | 3.57 | 3.57 |
| 343.39 | 3.41 | 3.41 |
| 354.34 | 1.83 | 1.83 |
| 370.41 | 2.00 | 2.00 |
| 382.40 | 2.52 | 2.52 |
| 339.38 | 2.42 | 2.42 |
| 283.31 | 3.74 | 3.74 |
| 325.35 | 2.52 | 2.52 |
| 401.49 | 4.90 | 4.90 |
| 431.51 | 4.91 | 4.91 |
| 311.36 | 2.99 | 2.99 |
| 325.39 | 3.38 | 3.38 |