Basic Information
ID: ALA1938154
Type: Binding
Description: Inhibition of PARP1 in rat PC12 cells assessed as NAD+ recovery at 1 uM pre-treated for 1 hr before hydrogen peroxide addition followed by washout and compound treated again for 1 hr relative to control
Organism: Rattus norvegicus
Cell type: PC-12
Activity Charts
Bioactivity
Activity Types for Assay ALA1938154
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 276.30 | 2.69 | 2.69 |
| 389.46 | 3.22 | 3.22 |
| 416.48 | 2.12 | 2.12 |
| 403.44 | 2.21 | 2.21 |
| 401.47 | 3.36 | 3.36 |
| 385.38 | 2.17 | 2.17 |
| 461.52 | 3.15 | 3.15 |
| 519.43 | 1.89 | 1.89 |
| 445.48 | 2.51 | 2.51 |
| 487.56 | 3.68 | 3.68 |
| 545.47 | 2.43 | 2.43 |
| 376.37 | 2.74 | 2.74 |
| 431.49 | 3.52 | 3.52 |
| 429.48 | 3.28 | 3.28 |
| 443.50 | 3.67 | 3.67 |
| 451.48 | 4.08 | 4.08 |
| 445.48 | 2.52 | 2.52 |
| 544.61 | 3.74 | 3.74 |
| 480.95 | 2.09 | 2.09 |
| 518.57 | 3.30 | 3.30 |
| 454.91 | 1.73 | 1.73 |
| 419.44 | 1.76 | 1.76 |
| 529.59 | 3.99 | 3.99 |
| 473.49 | 2.73 | 2.73 |
| 472.50 | 2.13 | 2.13 |
| 372.38 | 2.31 | 2.31 |
| 386.41 | 2.65 | 2.65 |