Basic Information
ID: ALA1938155
Type: Binding
Description: Inhibition of PARP1 in rat PC12 cells assessed as NAD+ recovery at 10 uM pre-treated for 1 hr before hydrogen peroxide addition followed by washout and compound treated again for 1 hr relative to 5H-phenanthridin-6-one
Organism: Rattus norvegicus
Cell type: PC-12
Activity Charts
Bioactivity
Activity Types for Assay ALA1938155
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 416.48 | 2.12 | 2.12 |
| 403.44 | 2.21 | 2.21 |
| 454.91 | 1.73 | 1.73 |
| 419.44 | 1.76 | 1.76 |
| 372.38 | 2.31 | 2.31 |