Assay Report Card

Basic Information

ID: ALA1941447

Type: Functional

Description: Antagonist activity at GluN2B/NMDA in FVB mouse CA1 pyramidal neurons assessed as reduction in NMDA-mediated inward current at 10 uM measured for 5 mins by whole-cell patch clamp assay in presence of glycine and tetrodotoxin

Organism: Mus musculus

Strain: FVB

Cell type: Pyramidal neuron

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
348.454.014.01
348.454.014.01