Basic Information
ID: ALA1941974
Type: Binding
Description: Inhibition of HIF1 in human LN229 cells after 1 hr preincubation under hypoxic condition measured after 24 hrs by luciferase reporter gene assay
Organism: Homo sapiens
Cell type: LN229
Activity Charts
Bioactivity
Activity Types for Assay ALA1941974
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 474.41 | 6.57 | 6.57 |
| 431.55 | 4.49 | 4.49 |
| 568.41 | 6.93 | 6.93 |
| 471.62 | 5.41 | 5.41 |
| 325.41 | 4.50 | 4.50 |
| 266.34 | 3.88 | 3.88 |
| 293.41 | 5.10 | 5.10 |
| 309.37 | 4.18 | 4.18 |
| 344.25 | 5.25 | 5.25 |
| 283.35 | 4.62 | 4.62 |
| 339.44 | 4.52 | 4.52 |
| 280.37 | 3.90 | 3.90 |
| 307.44 | 5.12 | 5.12 |
| 427.52 | 3.71 | 3.71 |
| 445.58 | 4.88 | 4.88 |
| 445.58 | 4.88 | 4.88 |
| 429.54 | 4.26 | 4.26 |
| 459.61 | 5.13 | 5.13 |
| 457.59 | 5.02 | 5.02 |
| 429.54 | 4.24 | 4.24 |
| 435.55 | 5.27 | 5.27 |
| 433.57 | 5.88 | 5.88 |
| 479.60 | 5.67 | 5.67 |
| 434.52 | 4.65 | 4.65 |
| 453.56 | 4.81 | 4.81 |
| 473.64 | 5.33 | 5.33 |
| 419.54 | 4.02 | 4.02 |
| 433.57 | 4.41 | 4.41 |
| 459.61 | 4.94 | 4.94 |
| 445.58 | 4.55 | 4.55 |
| 466.56 | 4.68 | 4.68 |
| 472.61 | 4.81 | 4.81 |
| 466.56 | 4.68 | 4.68 |
| 446.57 | 4.27 | 4.27 |
| 526.61 | 4.70 | 4.70 |
| 458.58 | 4.42 | 4.42 |
| 472.61 | 4.81 | 4.81 |
| 520.65 | 5.56 | 5.56 |
| 486.63 | 5.20 | 5.20 |
| 500.66 | 5.59 | 5.59 |
| 444.55 | 4.03 | 4.03 |
| 484.55 | 4.82 | 4.82 |
| 412.56 | 4.93 | 4.93 |
| 372.49 | 4.01 | 4.01 |
| 370.47 | 3.76 | 3.76 |
| 386.52 | 4.40 | 4.40 |
| 372.49 | 4.01 | 4.01 |
| 386.52 | 4.26 | 4.26 |
| 482.61 | 6.33 | 6.33 |
| 450.52 | 4.39 | 4.39 |
| 457.56 | 5.21 | 5.21 |
| 464.54 | 4.43 | 4.43 |
| 436.53 | 4.67 | 4.67 |
| 451.50 | 4.57 | 4.57 |
| 454.64 | 5.91 | 5.91 |
| 472.61 | 4.81 | 4.81 |