Basic Information
ID: ALA1942719
Type: Binding
Description: Inhibition of MK2-mediated HSP27 phosphorylation at Ser78 in LPS-stimulated human THP-1 cells pre-incubated for 60 mins before LPS treatment measured after 60 mins
Organism: Homo sapiens
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA1942719
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 381.86 | 4.26 | 4.26 |
| 472.98 | 5.25 | 5.25 |
| 393.87 | 4.17 | 4.17 |
| 384.44 | 3.38 | 3.38 |
| 416.91 | 4.77 | 4.77 |
| 407.48 | 3.98 | 3.98 |
| 417.90 | 4.16 | 4.16 |
| 408.47 | 3.38 | 3.38 |
| 401.45 | 3.65 | 3.65 |
| 430.94 | 5.07 | 5.07 |
| 431.93 | 4.47 | 4.47 |
| 432.91 | 4.75 | 4.75 |
| 409.87 | 4.15 | 4.15 |