Basic Information
ID: ALA1942828
Type: Functional
Description: Antagonist activity at mouse NPBWR1 expressed in CHO-K1 cells assessed as inhibition of hNPW23 and forskolin-stimulated cAMP production after 1 hr by TR-FRET assay
Format: BAO_0000219
Organism: Mus musculus
Cell type: CHO-K1
Target: Neuropeptides B/W receptor type 1(ALA1938219)
Document: ALA1938351
Antagonist activity at mouse NPBWR1 expressed in CHO-K1 cells assessed as inhibition of hNPW23 and forskolin-stimulated cAMP production after 1 hr by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1942828
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 539.15 | 5.76 | 5.76 |
| 538.16 | 6.36 | 6.36 |
| 504.70 | 5.10 | 5.10 |
| 539.15 | 5.76 | 5.76 |
| 539.15 | 5.76 | 5.76 |
| 539.15 | 5.76 | 5.76 |
| 518.73 | 5.41 | 5.41 |
| 572.70 | 6.12 | 6.12 |
| 534.73 | 5.11 | 5.11 |
| 529.71 | 4.98 | 4.98 |
| 510.73 | 5.17 | 5.17 |
| 589.63 | 5.93 | 5.93 |
| 579.71 | 5.58 | 5.58 |
| 560.79 | 6.32 | 6.32 |
| 544.72 | 5.85 | 5.85 |
| 543.74 | 5.58 | 5.58 |
| 525.12 | 5.20 | 5.20 |
| 509.12 | 5.75 | 5.75 |
| 553.17 | 5.93 | 5.93 |
| 551.16 | 5.69 | 5.69 |
| 565.18 | 6.08 | 6.08 |
| 588.02 | 6.51 | 6.51 |
| 614.05 | 6.83 | 6.83 |
| 614.05 | 6.83 | 6.83 |
| 614.05 | 6.83 | 6.83 |
| 565.18 | 6.08 | 6.08 |
| 568.14 | 5.83 | 5.83 |
| 557.59 | 6.58 | 6.58 |
| 541.14 | 6.06 | 6.06 |
| 537.17 | 6.23 | 6.23 |
| 558.75 | 6.02 | 6.02 |
| 570.76 | 6.17 | 6.17 |
| 557.76 | 5.76 | 5.76 |
| 569.78 | 5.90 | 5.90 |
| 586.83 | 6.64 | 6.64 |
| 605.75 | 5.90 | 5.90 |
| 616.65 | 5.64 | 5.64 |
| 584.79 | 6.48 | 6.48 |
| 588.75 | 6.31 | 6.31 |
| 588.75 | 6.31 | 6.31 |
| 587.77 | 6.04 | 6.04 |