Basic Information
ID: ALA1942830
Type: Functional
Description: Antagonist activity at human NPBWR1 expressed in CHO-K1 cells assessed as inhibition of hNPW23 and forskolin-stimulated cAMP production after 1 hr by TR-FRET assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: Neuropeptides B/W receptor type 1(ALA1293293)
Document: ALA1938351
Antagonist activity at human NPBWR1 expressed in CHO-K1 cells assessed as inhibition of hNPW23 and forskolin-stimulated cAMP production after 1 hr by TR-FRET assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1942830
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 539.15 | 5.76 | 5.76 |
| 558.75 | 6.02 | 6.02 |
| 570.76 | 6.17 | 6.17 |
| 557.76 | 5.76 | 5.76 |
| 569.78 | 5.90 | 5.90 |
| 586.83 | 6.64 | 6.64 |
| 605.75 | 5.90 | 5.90 |
| 616.65 | 5.64 | 5.64 |
| 584.79 | 6.48 | 6.48 |
| 588.75 | 6.31 | 6.31 |
| 588.75 | 6.31 | 6.31 |
| 587.77 | 6.04 | 6.04 |