Activation of EIF2alpha kinase in human CRL2351 cells assessed as reduction in eIF2-GTP-initiator methionine tRNA ternary complex measuring increase i...

Basic Information

ID: ALA1942915

Type: Binding

Description: Activation of EIF2alpha kinase in human CRL2351 cells assessed as reduction in eIF2-GTP-initiator methionine tRNA ternary complex measuring increase in firefly/renilla luciferase ratio at 40 uM after 16 hrs by dual luciferase reporter gene assay relative to control

Format: BAO_0000219

Organism: Homo sapiens

Target:  Eukaryotic translation initiation factor 2-alpha kinase 1(ALA6029)

Document:  ALA1938338

Activation of EIF2alpha kinase in human CRL2351 cells assessed as reduction in eIF2-GTP-initiator methionine tRNA ternary complex measuring increase in firefly/renilla luciferase ratio at 40 uM after 16 hrs by dual luciferase reporter gene assay relative to control: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
298.133.743.74