Basic Information
ID: ALA1942918
Type: Binding
Description: Activation of EIF2alpha kinase in human CRL2351 cells assessed as reduction in eIF2-GTP-initiator methionine tRNA ternary complex measuring increase in firefly/renilla luciferase ratio at 2.5 uM after 16 hrs by dual luciferase reporter gene assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Eukaryotic translation initiation factor 2-alpha kinase 1(ALA6029)
Document: ALA1938338
Activation of EIF2alpha kinase in human CRL2351 cells assessed as reduction in eIF2-GTP-initiator methionine tRNA ternary complex measuring increase in firefly/renilla luciferase ratio at 2.5 uM after 16 hrs by dual luciferase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1942918
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 417.14 | 6.68 | 6.68 |
| 484.24 | 7.41 | 7.41 |