Basic Information
ID: ALA1942919
Type: Binding
Description: Activation of EIF2alpha kinase in human CRL2351 cells assessed as reduction in eIF2-GTP-initiator methionine tRNA ternary complex measuring increase in firefly/renilla luciferase ratio at 5 uM after 16 hrs by dual luciferase reporter gene assay relative to control
Format: BAO_0000219
Organism: Homo sapiens
Target: Eukaryotic translation initiation factor 2-alpha kinase 1(ALA6029)
Document: ALA1938338
Activation of EIF2alpha kinase in human CRL2351 cells assessed as reduction in eIF2-GTP-initiator methionine tRNA ternary complex measuring increase in firefly/renilla luciferase ratio at 5 uM after 16 hrs by dual luciferase reporter gene assay relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA1942919
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 350.03 | 5.94 | 5.94 |
| 325.20 | 4.95 | 4.95 |
| 358.75 | 5.32 | 5.32 |
| 392.30 | 5.69 | 5.69 |