Assay Report Card

Basic Information

ID: ALA1943304

Type: Binding

Description: Activation of EIF2alpha kinase in human CRL2351 cells assessed as reduction in eIF2-GTP-initiator methionine tRNA ternary complex measuring increase in firefly/renilla luciferase ratio at 10 uM after 16 hrs by dual luciferase reporter gene assay relative to control

Organism: Homo sapiens

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
344.725.025.02
449.395.625.62
491.435.395.39
563.374.964.96