Basic Information
ID: ALA1944172
Type: Functional
Description: Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of 5H-dibenzo[b,e]azepine-10-carboxylic acid methyl ester-induced increase in intracellular calcium by Fluo4-AM based fluorometric assay
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA1944172
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 355.40 | 1.20 | 1.20 |
| 258.35 | 2.62 | 2.62 |
| 256.37 | 2.85 | 2.85 |
| 332.47 | 5.14 | 5.14 |
| 266.37 | 3.66 | 3.66 |
| 276.30 | 2.65 | 2.65 |
| 336.42 | 3.16 | 3.16 |
| 364.40 | 3.06 | 3.06 |
| 336.42 | 3.16 | 3.16 |
| 306.32 | 2.66 | 2.66 |
| 380.47 | 3.23 | 3.23 |
| 380.47 | 3.23 | 3.23 |
| 322.39 | 2.82 | 2.82 |
| 322.39 | 2.82 | 2.82 |
| 393.51 | 3.14 | 3.14 |
| 414.49 | 4.61 | 4.61 |
| 352.42 | 2.18 | 2.18 |
| 380.47 | 2.96 | 2.96 |
| 379.49 | 2.75 | 2.75 |
| 352.42 | 2.83 | 2.83 |
| 364.47 | 3.99 | 3.99 |
| 380.47 | 3.23 | 3.23 |
| 336.37 | 2.51 | 2.51 |
| 352.42 | 2.83 | 2.83 |
| 352.42 | 2.83 | 2.83 |
| 308.36 | 2.52 | 2.52 |
| 322.39 | 2.31 | 2.31 |
| 322.39 | 2.82 | 2.82 |
| 322.39 | 2.82 | 2.82 |
| 371.26 | 3.58 | 3.58 |
| 310.35 | 2.95 | 2.95 |
| 310.35 | 2.95 | 2.95 |
| 322.39 | 2.82 | 2.82 |
| 292.36 | 2.81 | 2.81 |
| 292.36 | 2.81 | 2.81 |
| 244.36 | 3.03 | 3.03 |
| 308.41 | 3.36 | 3.36 |
| 292.41 | 3.56 | 3.56 |
| 230.34 | 2.64 | 2.64 |
| 292.36 | 2.81 | 2.81 |
| 368.46 | 3.19 | 3.19 |