Assay Report Card

Basic Information

ID: ALA1944199

Type: Binding

Description: Binding affinity to GlyT1 in rat brain hippocampus at 0.03 to 0.04 nM preincubated for 20 mins in binding buffer before compound addition measured after 30 mins by autoradiography in presence of 0.01 mM NMDA receptor glycine site antagonist L-701,324 relative to control

Organism: Rattus norvegicus

Tissue: Hippocampus

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
500.325.275.27