Basic Information
ID: ALA1953081
Type: ADME
Description: Inhibition of recombinant human CYP3A4 in supersomes using midazolam as substrate after 5 mins by LC-MS/MS analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1953081
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.81 | 4.92 | 4.92 |
| 408.26 | 5.03 | 5.03 |
| 363.81 | 4.92 | 4.92 |
| 347.35 | 4.41 | 4.41 |
| 363.81 | 4.92 | 4.92 |
| 408.26 | 5.03 | 5.03 |
| 329.36 | 4.27 | 4.27 |
| 343.39 | 4.58 | 4.58 |
| 374.36 | 4.18 | 4.18 |
| 387.40 | 4.06 | 4.06 |
| 359.39 | 4.28 | 4.28 |
| 405.46 | 5.94 | 5.94 |
| 401.43 | 4.45 | 4.45 |
| 386.42 | 3.63 | 3.63 |
| 400.44 | 4.02 | 4.02 |
| 414.47 | 4.41 | 4.41 |
| 400.44 | 3.97 | 3.97 |
| 428.50 | 4.75 | 4.75 |
| 456.55 | 5.53 | 5.53 |
| 448.49 | 5.52 | 5.52 |
| 440.51 | 4.94 | 4.94 |
| 440.51 | 4.90 | 4.90 |
| 442.48 | 3.74 | 3.74 |
| 414.47 | 4.41 | 4.41 |
| 428.50 | 4.42 | 4.42 |
| 428.50 | 4.72 | 4.72 |
| 442.52 | 4.97 | 4.97 |
| 448.91 | 5.06 | 5.06 |
| 459.51 | 3.59 | 3.59 |
| 374.44 | 4.53 | 4.53 |
| 430.47 | 5.81 | 5.81 |
| 421.46 | 5.64 | 5.64 |
| 420.48 | 5.52 | 5.52 |
| 435.49 | 5.94 | 5.94 |
| 455.52 | 7.09 | 7.09 |
| 406.45 | 5.33 | 5.33 |
| 406.45 | 5.33 | 5.33 |
| 361.38 | 4.09 | 4.09 |
| 422.29 | 4.71 | 4.71 |