Basic Information
ID: ALA1953084
Type: ADME
Description: Inhibition of recombinant human CYP3A5 in supersomes using midazolam as substrate at 60 uM after 5 mins by LC-MS/MS analysis
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA1953084
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 363.81 | 4.92 | 4.92 |
| 343.39 | 4.58 | 4.58 |
| 387.40 | 4.06 | 4.06 |
| 359.39 | 4.28 | 4.28 |
| 401.43 | 4.45 | 4.45 |
| 373.37 | 3.97 | 3.97 |
| 386.42 | 3.63 | 3.63 |
| 414.47 | 4.41 | 4.41 |
| 448.49 | 5.52 | 5.52 |
| 428.50 | 4.42 | 4.42 |
| 413.48 | 5.01 | 5.01 |
| 459.51 | 3.59 | 3.59 |
| 390.45 | 3.51 | 3.51 |
| 389.46 | 4.11 | 4.11 |
| 420.48 | 5.52 | 5.52 |
| 406.45 | 5.33 | 5.33 |
| 406.45 | 5.33 | 5.33 |